產(chǎn)品編號 | bs-13833R-BF350 |
英文名稱1 | Rabbit Anti-CENPBD1/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的CENPBD1蛋白抗體 |
別 名 | CENP1_HUMAN; CENPB DNA binding domains containing 1; CENPB DNA-binding domain-containing protein 1; CENPBD1; FLJ23771; FLJ31569; MGC13198; MGC16385. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 結(jié)合蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 21kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CENPBD1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: CENPBD1 is a 187 amino acid nuclear protein that contains one HTH CENPB-type DNA-binding domain and a HTH psq-type DNA-binding domain. The gene encoding CENPBD1 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. Subcellular Location: Nucleus. Similarity: Contains 1 HTH CENPB-type DNA-binding domain. Contains 1 HTH psq-type DNA-binding domain. Database links: Entrez Gene: 92806 Human SwissProt: B2RD01 Human Unigene: 513832 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |