產(chǎn)品編號(hào) | bs-12110R-Gold |
英文名稱1 | Rabbit Anti-P2RX6/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的三磷酸腺苷受體P2X6抗體 |
別 名 | ATP receptor; P2RX6; P2RX6_HUMAN; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X like 1; Purinergic receptor P2X-like 1; Skeletal muscle expressed P2X. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 通道蛋白 細(xì)胞膜受體 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 49kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human P2RX6 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. Function: Receptor for ATP that acts as a ligand-gated ion channel. Subunit: Functional P2XRs are organized as homomeric and heteromeric trimers Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed predominantly in skeletal muscle. Similarity: Belongs to the P2X receptor family. Database links: Entrez Gene: 9127 Human Entrez Gene: 18440 Mouse Omim: 608077 Human SwissProt: O15547 Human SwissProt: O54803 Mouse Unigene: 113275 Human Unigene: 8032 Mouse Unigene: 10258 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |