產(chǎn)品編號 | bs-11916R-Gold |
英文名稱1 | Rabbit Anti-Neugrin/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的突觸生長相關(guān)蛋白抗體 |
別 名 | DSC92; FI58Gm; Mesenchymal stem cell protein DSC92; Neugrin; Neugrin neurite outgrowth associated; Neurite outgrowth associated protein; Neurite outgrowth-associated protein; Ngrn; NGRN_HUMAN; Spinal cord-derived protein FI58G. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Neugrin |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Neugrin, also known as NGRN, mesenchymal stem cell protein DSC92, neurite outgrowth-associated protein or spinal cord-derived protein FI58G, is a 291 amino acid protein that plays a role in neuronal differentiation and belongs to the neugrin family. As both a secreted and nuclear protein, neugrin exists as two alternatively spliced isoforms and is highly expressed in skeletal muscle, brain and heart. Neugrin is upregulated in neuroblastostoma cells by retinoic acid treatment and is encoded by a gene that maps to human chromosome 15q26.1. Chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: May be involved in neuronal differentiation. Subcellular Location: Nucleus. Secreted. Tissue Specificity: Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells. Similarity: Belongs to the neugrin family. Database links: UniProtKB/Swiss-Prot: Q9NPE2.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |