| 產(chǎn)品編號(hào) | bs-5744R-Gold |
| 英文名稱1 | Rabbit Anti-CABLES2/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的細(xì)胞周期蛋白依賴性激酶CABLES2抗體 |
| 別 名 | CABLES 2; Cdk5 and Abl enzyme substrate 2; Ik3 2 ; Interactor with CDK3 2; C20orf150; CABL2_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 52kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CABLES2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: CABLES2 is a proapoptotic factor involved in both p53-mediated and p53-independent apoptotic pathways. ik3-1/CABLES1, a closely related molecule, has been identified to be a candidate tumor suppressor for colon and head/neck cancers. The exact function of this protein is unknown, but it is probably involved in G1-S cell cycle transition. CABLES2 binds to CDK3, CDK5 and ABL1. Function: Unknown. Probably involved in G1-S cell cycle transition. Subunit: Binds to CDK3, CDK5 and ABL1. The C-terminal cyclin-box-like region binds to CDK5 (By similarity). Similarity: Belongs to the cyclin family. Database links: UniProtKB/Swiss-Prot: Q9BTV7.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
