產(chǎn)品編號(hào) | bs-4245R-Gold |
英文名稱1 | Rabbit Anti-LONP1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的線粒體離子肽酶1抗體 |
別 名 | Serine protease 15; hLON ATP dependent protease; Lon protease like protein; LonHS; LONP; PIM1; PRSS15; hLON; LON; lon peptidase 1, mitochondrial; LON protease; Mitochondrial ATP dependent protease Lon; Mitochondrial Ion peptidase 1; Protease serine 15. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 免疫學(xué) 染色質(zhì)和核信號(hào) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 98kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LONP1 (375-420aa) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: LONP1 encodes a mitochondrial matrix protein in the Lon family of ATP dependent proteases. It binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. Subunit: Homohexamer or homoheptamer. Organized in a ring with a central cavity. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with PEO1 and mitochondrial DNA polymerase subunit POLG. Subcellular Location: Mitochondrion matrix. Tissue Specificity: Duodenum, heart, lung and liver, but not thymus. Similarity: Belongs to the peptidase S16 family. Contains 1 Lon domain. Database links: Entrez Gene: 9361 Human Entrez Gene: 74142 Mouse Omim: 605490 Human SwissProt: P36776 Human SwissProt: Q8CGK3 Mouse Unigene: 350265 Human Unigene: 329136 Mouse Unigene: 146805 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |