產(chǎn)品編號 | bs-0848R-Gold |
英文名稱1 | Rabbit Anti-CSP/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的環(huán)子孢子蛋白(約氏瘧原蟲)抗體 |
別 名 | circumsporozoite protein (Plasmodium yoelii); Circumsporozoite protein; CS; CSP_PLAYO. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 昆蟲 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 37kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from the middle of Plasmodium yoelii CSP |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: No data available. Function: The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). Similarity: Belongs to the plasmodium circumsporozoite protein family. Contains 1 TSP type-1 domain. Database links: UniProtKB/Swiss-Prot: P06914.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 瘧原蟲的保護(hù)性抗原主要在蟲體表面,統(tǒng)稱表面抗原。在瘧原蟲生活史的發(fā)育各期,既有共同抗原,又有期特異性抗原,近年來經(jīng)研究發(fā)現(xiàn)了惡性瘧原蟲和間日瘧原蟲的配子表面的保護(hù)性抗原,已證明成熟子孢子體外附著的環(huán)子孢子蛋白(Circumsporozoite protein,CSP)具有明顯的抗原性。 紅內(nèi)期瘧原蟲的不同發(fā)育階段,其抗原的質(zhì)和量均有變化,并可在被寄生的紅細(xì)胞膜上表露出來。裂殖子和子孢子均屬游離的瘧原蟲,因此誘導(dǎo)的宿主免疫均較明顯。已知有許多瘧原蟲抗體可作用于裂殖子,使裂殖子凝集,阻止裂殖體釋放裂殖子。裂殖子表面抗原與其侵入紅細(xì)胞有關(guān)。 |