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Rabbit Anti-phospho-JunB (Ser259)/BF555 Conjugated antibody (bs-5464R-BF555)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5464R-BF555
英文名稱1 Rabbit Anti-phospho-JunB (Ser259)/BF555 Conjugated antibody
中文名稱 BF555標記的磷酸化活化蛋白激酶B抗體
別    名 JunB (phospho S259); JunB (phospho S259); p-JunB (phospho S259); JunB (phospho-Ser259); JunB (phospho Ser259); JunB (phospho-S259); p-JunB (Ser259); p-JunB (S259); Transcription factor jun-B; AP 1; AP1; Jun B; Jun B proto oncogene; Jun B protooncogene; JunB proto oncogene; JunB protoncogene 9; JunB protooncogene; Transcription factor jun B; Transcription factor junB; JUNB_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領域 腫瘤  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human JunB around the phosphorylation site of Ser259 [PV(p-S)PI]
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Function:
Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Subunit:
Binds DNA as a homodimer or as a heterodimer with another member of the Jun/Fos family. Interacts with ITCH (via its WW domains).

Subcellular Location:
Nucleus.

Post-translational modifications:
Ubiquitinated by ITCH, leading to its degradation.

Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

Database links:

Entrez Gene: 3726 Human

Entrez Gene: 16477 Mouse

Entrez Gene: 24517 Rat

Omim: 165161 Human

SwissProt: P17275 Human

SwissProt: P09450 Mouse

SwissProt: P24898 Rat

Unigene: 25292 Human

Unigene: 1167 Mouse

Unigene: 470093 Mouse

Unigene: 15806 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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