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Rabbit Anti-ZNF268/Gold Conjugated antibody (bs-0625R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-0625R-Gold
英文名稱1 Rabbit Anti-ZNF268/Gold Conjugated antibody
中文名稱 膠體金標記的鋅指脂蛋白抗體
別    名 zinc finger protein ZNF268; zinc finger protein 268 isoform c; zinc finger protein 3; zinc finger protein HZF3; HZF3; MGC126498; ZN268_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 染色質和核信號  信號轉導  轉錄調節(jié)因子  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 108kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF268
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 268 (ZNF268), also known as zinc finger protein 3 or HZF3, is a 947 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. ZNF268 contains 24 C2H2-type zinc fingers and one KRAB domain. Localized to the nucleus, ZNF268 is involved in transcriptional regulation and is highly expressed in three to five week old embryos. ZNF268 has been implicated in human leukemia, due to the identification of an alternatively spliced form in leukemia patients. Two named isoforms of ZNF268 exist as a result of alternative splicing events.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus (Probable).

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 24 C2H2-type zinc fingers.
Contains 1 KRAB domain.

Database links:

Entrez Gene: 10795 Human

Omim: 604753 Human

SwissProt: Q14587 Human

Unigene: 124047 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

鋅指基因家族是人體中最大的基因家族,它參與細胞分化、胚胎發(fā)育,并與許多疾病的發(fā)生相關。
人類ZNF268基因是一個在人胚肝中特異性表達的C2H2型鋅指基因,并可能在人的早期肝臟發(fā)育中起重要作用.
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