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Rabbit Anti-SRP68/Gold Conjugated antibody (bs-2381R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2381R-Gold
英文名稱1 Rabbit Anti-SRP68/Gold Conjugated antibody
中文名稱 膠體金標記的信號識別顆粒抗體
別    名 Signal recognition particle 68 kDa; Signal recognition particle subunit SRP68; Signal recognition particle 68 kDa protein; SRP 68; Srp68; SRP68_HUMAN.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 免疫學  染色質(zhì)和核信號  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SRP68
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.

Function:
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.

Subunit:
Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

Subcellular Location:
Cytoplasm. Nucleus, nucleolus.

Similarity:
Belongs to the SRP68 family.

Database links:

Entrez Gene: 6730 Human

Entrez Gene: 217337 Mouse

Entrez Gene: 363707 Rat

Omim: 604858 Human

SwissProt: Q9UHB9 Human

SwissProt: Q8BMA6 Mouse

Unigene: 514495 Human

Unigene: 29655 Mouse

Unigene: 68 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

信號識別顆粒(Signalrecognitionparticle,SRP)是介導蛋白識別轉(zhuǎn)運其中普遍存在的機制之一,細胞內(nèi)蛋白質(zhì)的定向轉(zhuǎn)移是蛋白質(zhì)質(zhì)量數(shù)量控制體系的一個重要環(huán)節(jié),SRP對參與這一過程的功能基因和蛋白,尤其是蛋白的靶向輸送機制的研究對揭示細胞的分化、代謝和病變具有重大的理論意義.
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