產(chǎn)品編號 | bs-9300R-Gold |
英文名稱1 | Rabbit Anti-NNP1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的新型核蛋白質(zhì)1抗體 |
別 名 | NNP 1; NNP-1; NNP1; Nnp1 homolog nucleolar protein; Novel nuclear protein 1; Nucleolar protein Nop52; Protein NNP 1; Protein NNP1; Ribosomal RNA processing 1 homolog; Ribosomal RNA processing protein 1 homolog A; rrp1; RRP1 like protein; RRP1-like protein; RRP1_HUMAN; RRP1A. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞周期蛋白 細(xì)胞分化 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 53kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NNP1/RRP1 like protein |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Novel nuclear protein 1 (NNP-1), also known as RRP1-like protein or Nucleolar protein Nop52, is a 461 amino acid protein belonging to the RRP1 family. Localized to the nucleolus, NNP-1 has simian virus 40-type and bipartite nuclear localization signals and four coiled-coil domains within its C-terminal region. NNP-1 has been found to play an important role in the generation of 28S rRNA in the late processing steps of ribosome biogenesis. At the end of mitosis, nucleolar proteins assemble in a sequential order during the rebuilding of the nucleolus. NNP-1 assembles after Fibrillarin and C23, and simultaneously with B23 and POP1 in the prenucleolar body pathway. Function: Plays a critical role in the generation of 28S rRNA. Subunit: Interacts with C1QBP. Subcellular Location: Nucleus, nucleolus. Tissue Specificity: Ubiquitously expressed in fetal and adult tissues. Similarity: Belongs to the RRP1 family. Database links: Entrez Gene: 23076 Human Entrez Gene: 72462 Mouse Omim: 610654 Human SwissProt: Q14684 Human SwissProt: Q91YK2 Mouse Unigene: 654727 Human Unigene: 54275 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |