| 產(chǎn)品編號(hào) | bs-9266R-Gold |
| 英文名稱1 | Rabbit Anti-USP9X/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的泛素特異性蛋白酶9X抗體 |
| 別 名 | X chromosome; X-linked; Deubiquitinating enzyme FAF X; Deubiquitinating enzyme FAF-X; DFFRX; Fafl; Fam; Fat facets homolog; Fat facets in mammals; Fat facets protein related X linked; Fat facets protein related X-linked; Fat facets protein-related; hFAM; Probable ubiquitin carboxyl terminal hydrolase FAF X; Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Ubiquitin carboxyl-terminal hydrolase FAM; Ubiquitin specific processing protease FAF X; Ubiquitin specific protease 9 X chromosome; Ubiquitin thiolesterase FAF X; Ubiquitin thiolesterase FAF-X; Ubiquitin-specific processing protease FAF-X; Ubiquitin-specific protease 9; Ubiquitin-specific protease 9 X chromosome; Ubiquitin-specific-processing protease FAF-X; USP9 (gene name); Usp9x; USP9X_HUMAN |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 292kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from hu USP9X |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Function: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Subunit: Interacts with SMAD4, MARK4, NUAK1 and BIRC5/survivin. Subcellular Location: Cytoplasm. Tissue Specificity: Widely expressed in embryonic and adult tissues. Similarity: Belongs to the peptidase C19 family. Database links: Entrez Gene: 8239 Human Entrez Gene: 22284 Mouse Omim: 300072 Human SwissProt: Q93008 Human SwissProt: P70398 Mouse Unigene: 77578 Human Unigene: 242646 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
