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Rabbit Anti-SERPINB11/Cy7 Conjugated antibody (bs-9212R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9212R-Cy7
英文名稱1 Rabbit Anti-SERPINB11/Cy7 Conjugated antibody
中文名稱 Cy7標記的絲氨酸蛋白酶抑制劑B11抗體
別    名 EPIPIN; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 11 antibody Serpin B11 antibody Serpin peptidase inhibitor clade B (ovalbumin) member 11 antibody SERPINB11d antibody SERPINB11e antibody SERPINB11f; SPB11_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SERPINB11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SerpinB11 (serpin peptidase inhibitor, clade B (ovalbumin), member 11), also known as EPIPIN or SERPIN11, is a 392 amino acid cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family. Like other members of the serpin family, SerpinB11 has been identified as a noninhibitory intracellular protein. The gene encoding SerpinB11 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

Function:
Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Detected in a restricted number of tissues, including lung, placenta, prostate, and tonsil.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

Database links:

Entrez Gene: 89778 Human

SwissProt: Q96P15 Human

Unigene: 350958 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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