產品編號 | bs-0280R-FITC |
英文名稱1 | Rabbit Anti-PLGF/FITC Conjugated antibody |
中文名稱 | FITC標記的胎盤生長因子抗體 |
別 名 | Placenta growth factor; PGF; PGFL; PIGF; Placental growth factor vascular endothelial growth factor related protein; PlGF 2; PLGF; PlGF2; PLGF_MOUSE; Vascular endothelial growth factor related protein. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 腫瘤 細胞生物 免疫學 神經生物學 生長因子和激素 轉錄調節(jié)因子 細胞表面分子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Mouse, Rat, Pig, ) |
產品應用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 16kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse PLGF |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產品介紹 |
background: This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011] Function: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Subunit: Antiparallel homodimer; disulfide-linked. Also found as heterodimer with VEGFA/VEGF. Subcellular Location: Secreted. The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin. Tissue Specificity: While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas. Post-translational modifications: N-glycosylated. Similarity: Belongs to the PDGF/VEGF growth factor family. Database links: Entrez Gene: 5228 Human Entrez Gene: 18654 Mouse Omim: 601121 Human SwissProt: P49763 Human SwissProt: P49764 Mouse Unigene: 252820 Human Unigene: 4809 Mouse Unigene: 6960 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PLGF胎盤生長因子是血管生長因子家族成員之一(又稱:胎盤型血管內皮細胞生長因子),是動脈粥樣硬化斑塊不穩(wěn)定的主要炎性激活物,因此它可作為ACS患者風險預測的生物學標志物.尿胎盤生長因子水平可預測先兆子癇危險.研究人員發(fā)現(xiàn),在疾病發(fā)作前的6到8周,先兆子癇患者尿液中的胎盤生長因子水平急劇下降,這種新的尿檢方法使提前1到2個月預測先兆子癇成為可能。亦有研究人員正在從事胎盤生長因子與肺氣腫,胃癌,腸癌等方面的研究。 |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |