產(chǎn)品編號(hào) | bs-1119R-HRP |
英文名稱(chēng)1 | Rabbit Anti-PAF/HRP Conjugated antibody |
中文名稱(chēng) | 辣根過(guò)氧化物酶標(biāo)記的血小板活化因子抗體 |
別 名 | platelet-activating factor; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate; 2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine; 1-hexadecyl-2-acetyl, PAF(C16. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul |
產(chǎn)品類(lèi)型 | 小分子抗體 |
研究領(lǐng)域 | 藥物及化合物 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 0.524kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated PAF |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Platelet-activating factor, a compound that reduces inflammation by increasing permeability of blood vessels and contracting various involuntary muscles such as those in airways. It is a phospholipid with a wide range of proinflammatory actions, is immediately degraded and inactivated in vivo by PAF acetylhydrolase. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 血小板活化因子(platelet-activating factor,PAF)是一種內(nèi)源性具有生物活性的磷脂。由中性粒細(xì)胞、血小板、肥大細(xì)胞、內(nèi)皮細(xì)胞和巨噬細(xì)胞產(chǎn)生。除早期發(fā)現(xiàn)它有強(qiáng)烈引起血小板聚集和脫顆粒作用外,近年來(lái)的研究發(fā)現(xiàn)它還具有廣泛的生物活性,作為一種獨(dú)特的細(xì)胞因子參與體內(nèi)多種生理、病理過(guò)程,包括激活中性粒細(xì)胞,使其聚集、趨化、釋放氧自由基和白三烯,抑制T細(xì)胞增殖,刺激B細(xì)胞合成IgG和IgE,抑制心肌收縮力,增加血管通透性,引起體循環(huán)血壓下降和肺動(dòng)脈高壓等。由于它具有廣泛的高強(qiáng)度的生物活性,故PAF被認(rèn)為是與過(guò)敏反應(yīng)有關(guān)的關(guān)鍵性介質(zhì)之一。 |