| 產(chǎn)品編號(hào) | bs-7885R-FITC |
| 英文名稱1 | Rabbit Anti-CCNDBP1/FITC Conjugated antibody |
| 中文名稱 | FITC標(biāo)記的周期素D結(jié)合蛋白1抗體 |
| 別 名 | Maternal inhibition of differentiation; SECC 8; SSEC 8; CCDB1_HUMAN; CCNDBP 1; Ccndbp1; Cyclin D type binding protein 1; Cyclin-D1-binding protein 1; D type cyclin interacting protein 1; DIP 1; DIP1; GCIP; Grap 2 and cyclin D interacting protein; Grap 2 cyclin D interacting protein GCIP; Grap 2 cyclin interacting protein; Grap2 and cyclin D interacting protein; Grap2 and cyclin-D-interacting protein; Grap2 cyclin D interacting protein GCIP; Grap2 cyclin interacting protein; HHM protein; Human homolog of Maid; MAID; MAID protein; Stage specific embryonic cDNA 8. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 細(xì)胞分化 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCNDBP1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas. Function: May negatively regulate cell cycle progression. May actat least in part via inhibition of the cyclin-D1/CDK4 complex,thereby preventing phosphorylation of RB1 and blockingE2F-dependent transcription. Subunit: Interacts with CCND1 and GRAP2. May also interact withCOPS5, RPLP0, SIRT6, SYF2 and TCF3. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Ubiquitously expressed. Expression isdown-regulated in a variety of tumor types including breast, colon,prostate and rectal tumors, and is up-regulated in certain hepaticcarcinomas. Post-translational modifications: Phosphorylated. Similarity: Belongs to the CCNDBP1 family. Database links: UniProtKB/Swiss-Prot: O95273.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
