| 產(chǎn)品編號(hào) | bs-7780R-Gold |
| 英文名稱1 | Rabbit Anti-CAPH/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的染色體相關(guān)蛋白H抗體 |
| 別 名 | Barren Drosophila Homolog of 1; Barren homolog protein 1; BRRN; CAP H; CAPH; Chromosome associated protein H; Condensin complex subunit 2; Condensin subunit 2; Condesin; HCAP H; mCAP H; NCAPH; Non SMC condensin I complex subunit H; XCAP H homolog; CND2_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 82kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BRRN1/CAPH |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Subunit: Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: NCAPH/BRRN1, NCAPD2/CAPD2 and NCAPG. Subcellular Location: CNucleus. Cytoplasm. Chromosome. Tissue Specificity: Widely expressed at low level. Expressed in proliferating cells. Post-translational modifications: Phosphorylated by CDK1. Its phosphorylation, as well as that of NCAPD2 and NCAPG subunits, activates the condensin complex and is required for chromosome condensation (By similarity). Similarity: Belongs to the CND2 (condensin subunit 2) family. Database links: UniProtKB/Swiss-Prot: Q15003.3 Entrez Gene: 23397 Human Entrez Gene: 215387 Mouse Omim: 602332 Human SwissProt: Q15003 Human SwissProt: Q8C156 Mouse Unigene: 308045 Human Unigene: 29786 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
