產(chǎn)品編號(hào) | bs-6394R-PE |
英文名稱1 | Rabbit Anti-Quiescin Q6/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的巰基氧化酶1抗體 |
別 名 | hQSOX; Human quiescin (Q6) mRNA, partial cds; Q6 antibody QSCN6; QSOX1; QSOX1_HUMAN; Quiescin Q6 sulfhydryl oxidase 1; Skin sulfhydryl oxidase; Sox; Sulfhydryl oxidase 1; Sulfhydryl oxidase 1 precursor. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 細(xì)胞周期蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 80kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Quiescin Q6/QSOX1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. Function: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation. Subunit: Monomer. Subcellular Location: Isoform 1: Golgi apparatus membrane; Single-pass membrane protein. Isoform 2: Secreted, extracellular space. Note=Found in the extracellular medium of quiescent cells but is not found in proliferating cells. Similarity: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family. Contains 1 ERV/ALR sulfhydryl oxidase domain. Contains 1 thioredoxin domain. Database links: Entrez Gene: 5768 Human Entrez Gene: 104009 Mouse Omim: 603120 Human SwissProt: O00391 Human SwissProt: Q8BND5 Mouse Unigene: 518374 Human Unigene: 719176 Human Unigene: 27035 Mouse Unigene: 44920 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |