| 產(chǎn)品編號 | bs-6382R-APC |
| 英文名稱1 | Rabbit Anti-PTK5/FRK/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的胃腸道相關(guān)酪氨酸激酶抗體（蛋白酪氨酸激酶5） |
| 別 名 | Beta cell Src homology tyrosine kinase; BSK; BSK/IYK; C85044; Frk; Frk fyn related kinase; FRK_HUMAN; FYN related kinase; FYN-related kinase; GASK; Gastrointestinal associated kinase; Gastrointestinal associated tyrosine kinase; GTK; Intestine tyrosine kinase; Nuclear tyrosine protein kinase RAK; Protein-tyrosine kinase 5; PTK5; RAK; Tyrosine protein kinase FRK; Tyrosine-protein kinase FRK. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 58kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FRK/PTK5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]. Function: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. Subunit: Interacts (via the SH3-domain) with PTEN. Interacts with RB1. Subcellular Location: Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery. Tissue Specificity: Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon. Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. Database links: Entrez Gene: 2444 Human Entrez Gene: 14302 Mouse Omim: 606573 Human SwissProt: P42685 Human SwissProt: Q922K9 Mouse Unigene: 89426 Human Unigene: 332432 Mouse Unigene: 10556 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
