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Rabbit Anti-BCCIP/RBITC Conjugated antibody (bs-7679R-RBITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7679R-RBITC
英文名稱1 Rabbit Anti-BCCIP/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的乳腺癌易感基因2和p21蛋白抑制因子抗體
別    名 bccip; BCCIP_HUMAN; BCCIPalpha; BCCIPbeta; BRCA2 and CDKN1A interacting protein; BRCA2 and CDKN1A-interacting protein; BRCA2 and Cip1/p21 interacting protein; Cdk inhibitor p21 binding protein; P21 and CDK associated protein 1; P21- and CDK-associated protein 1; Protein TOK-1; Protein TOK1; TOK 1; TOK 1alpha; TOK 1beta; TOK1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞周期蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BCCIP/TOK1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
FunctionMay promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining.


Function:
May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).

Subunit:
Interacts with BRCA2, CDKN1A and MTDH/LYRIC.

Subcellular Location:
Nucleus. Note=Colocalizes with BRCA2 in discrete nuclear foci.

Tissue Specificity:
Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.

Similarity:
Belongs to the BCP1 family.

Database links:

Entrez Gene: 56647 Human

Omim: 611883 Human

SwissProt: Q9P287 Human

Unigene: 370292 Human

Unigene: 715543 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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