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Rabbit Anti-P15RS/Cy7 Conjugated antibody (bs-6391R-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6391R-Cy7
英文名稱1 Rabbit Anti-P15RS/Cy7 Conjugated antibody
中文名稱 Cy7標記的細胞周期依賴性激酶抑制相關蛋白抗體
別    名 Cyclin dependent kinase 2B inhibitor related protein; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein); Cyclin dependent kinase inhibitor 2B related protein; Cyclin dependent kinase inhibitor related protein; Hypothetical protein FLJ10656; p15INK4B related protein; Putative uncharacterized protein P15RS; Regulation of nuclear pre mRNA domain containing 1A; RPRD1A; RPR1A_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RPRD1A/P15RS
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
P15RS is upregulated in cells overexpressing cyclin-dependent kinase inhibitor p15(INK4b) (CDKN2B; MIM 600431) and may have a role in cell cycle regulation

Function:
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.

Subunit:
Associates with the RNA polymerase II complex.

Similarity:
Belongs to the UPF0400 (RTT103) family.
Contains 1 CID domain.

Database links:

Entrez Gene: 420953 Chicken

Entrez Gene: 504355 Cow

Entrez Gene: 55197 Human

Entrez Gene: 225283 Mouse

Omim: 610347 Human

SwissProt: Q5ZM30 Chicken

SwissProt: Q0P5J9 Cow

SwissProt: Q96P16 Human

SwissProt: Q8VDS4 Mouse

Unigene: 464912 Human

Unigene: 28427 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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