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Rabbit Anti-RHBDD3/PE-Cy7 Conjugated antibody (bs-7566R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7566R-PE-Cy7
英文名稱1 Rabbit Anti-RHBDD3/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的垂體瘤細胞凋亡抗體
別    名 C22orf3; HS984G1A; Pituitary tumor apoptosis; PTAG; RHBD3_HUMAN; RHBDD3; Rhomboid domain containing 3; Rhomboid domain-containing protein 3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  神經(jīng)生物學  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RHBDD3 (101-200aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
PTAG is a novel 386 amino acid multi-pass membrane protein that contains one UBA domain and augments drug-induced apoptosis. Cells lacking PTAG have a reduced apoptotic response, thereby causing a predisposition to cell malignancy and resistance to chemotherapeutic interventions, and PTAG plays a role in colorectal tumorigenesis as the majority of primary colorectal tumors lack the PTAG gene. Encoded by a gene located on human chromosome 22, PTAG is often co-expressed with EWS (ewing sarcoma breakpoint region 1), a gene located directly downstream of PTAG.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Similarity:
Contains 1 UBA domain

Database links:

Entrez Gene: 25807 Human

Entrez Gene: 279766 Mouse

Entrez Gene: 289753 Rat

SwissProt: Q9Y3P4 Human

SwissProt: Q8BP97 Mouse

SwissProt: Q642B3 Rat

Unigene: 106730 Human

Unigene: 260866 Mouse

Unigene: 9606 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

RHBDD3分子是一個全新的TLR信號途徑的負向調(diào)控蛋白分子,是一個能夠顯著抑制自身免疫性疾病發(fā)生的效應(yīng)分子,RHBDD3控制機體避免發(fā)生過度的免疫應(yīng)答、防止自身免疫性疾病的發(fā)生具有重要意義。
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