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Rabbit Anti-AUP1/BF350 Conjugated antibody (bs-7550R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7550R-BF350
英文名稱1 Rabbit Anti-AUP1/BF350 Conjugated antibody
中文名稱 BF350標記的原始廣泛存在蛋白1抗體
別    名 AA589454; AUP 1; AUP1; AUP1_HUMAN; Ancient ubiquitous protein 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AUP1/Ancient ubiquitous protein 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ancient ubiquitous protein 1 (AUP1) contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. It has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits.

Function:
May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.

Subunit:
Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1. Interacts with the cytoplasmic tail of ITGA2B, ITGA1, ITGA2, ITGA5, ITGAV and ITGAM.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side.

Tissue Specificity:
Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain.

Similarity:
Belongs to the AUP1 family.
Contains 1 CUE domain.

Database links:

Entrez Gene: 550 Human

Entrez Gene: 11993 Mouse

Entrez Gene: 680423 Rat

Omim: 602434 Human

SwissProt: Q9Y679 Human

SwissProt: P70295 Mouse

SwissProt: A1L134 Rat

Unigene: 411480 Human

Unigene: 386752 Mouse

Unigene: 198163 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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