| 產(chǎn)品編號 | bs-7550R-Gold |
| 英文名稱1 | Rabbit Anti-AUP1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的原始廣泛存在蛋白1抗體 |
| 別 名 | AA589454; AUP 1; AUP1; AUP1_HUMAN; Ancient ubiquitous protein 1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 細(xì)胞周期蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AUP1/Ancient ubiquitous protein 1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: Ancient ubiquitous protein 1 (AUP1) contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. It has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. Function: May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. Subunit: Identified in a complex that contains SEL1L, OS9, FAF2/UBXD8, UBE2J1/UBC6E and AUP1. Interacts with the cytoplasmic tail of ITGA2B, ITGA1, ITGA2, ITGA5, ITGAV and ITGAM. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type III membrane protein; Cytoplasmic side. Tissue Specificity: Detected in blood platelets and leukocytes (at protein level). Ubiquitous. Highly expressed in placenta, liver, kidney, skeletal muscle, heart and brain. Similarity: Belongs to the AUP1 family. Contains 1 CUE domain. Database links: Entrez Gene: 550 Human Entrez Gene: 11993 Mouse Omim: 602434 Human SwissProt: Q9Y679 Human SwissProt: P70295 Mouse Unigene: 411480 Human Unigene: 386752 Mouse Unigene: 198163 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
