產(chǎn)品編號(hào) | bs-1200R-Gold |
英文名稱1 | Rabbit Anti-Omgp/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的少突細(xì)胞髓磷脂糖蛋白抗體 |
別 名 | olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Cow, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 43kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Omgp |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin. Function: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. Subunit: Binds to RTN4R. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Oligodendrocytes and myelin of the central nervous system. Post-translational modifications: O-glycosylated in its Ser/Thr-rich repeat domain (Potential). Similarity: Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. Database links: Entrez Gene: 4974 Human Entrez Gene: 100172122 Orangutan Omim: 164345 Human SwissProt: P23515 Human Unigene: 113874 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. OMgp也是髓鞘糖蛋白的一種,在發(fā)育期促進(jìn)軸突生長(zhǎng),成熟期抑制軸突生長(zhǎng).其抑制作用主要由髓鞘來源的抑制分子的共同受體NgR介導(dǎo),在神經(jīng)營(yíng)養(yǎng)因子受體p75NTR以及小GTP酶Rho等信號(hào)分子的共同參與下完成. |