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Rabbit Anti-GIP/Gold Conjugated antibody (bs-0098R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0098R-Gold
英文名稱1 Rabbit Anti-GIP/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的胃泌素抑制肽抗體
別    名 Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic polypeptide; Incretin hormone.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Pig, Cow, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 5/17kDakDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion.

Function:
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.

Subcellular Location:
Secreted.

Similarity:
Belongs to the glucagon family.

Database links:

Entrez Gene: 2695 Human

Omim: 137240 Human

SwissProt: P09681 Human

Unigene: 1454 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胃泌素抑制肽(GIP)是胃腸道的一種由42個(gè)氨基酸組成的多肽激素,又稱為葡萄糖依賴性促胰島素多肽(glucose-dependent insulinotropic peptide,GIP)他強(qiáng)烈抑制胃分泌和運(yùn)動(dòng),也可調(diào)節(jié)胰島素的釋放。GIP屬于Glucagon家族成員。
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