產(chǎn)品編號 | bs-4062R-Gold |
英文名稱1 | Rabbit Anti-Glycerol kinase/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的甘油激酶抗體 |
別 名 | ATP glycerol 3 phosphotransferase; GK; GK1; GKD; Glycerokinase; Glycerol kinase; Glycerol kinase deficiency; ATP:glycerol 3-phosphotransferase; GLPK_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 61kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Glycerol kinase |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway. Function: Key enzyme in the regulation of glycerol uptake and metabolism. Subcellular Location: Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm. Tissue Specificity: Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver. DISEASE: Defects in GK are the cause of GK deficiency (GKD) [MIM:307030]. This disease can be either symptomatic with episodic metabolic and CNS decompensation or asymptomatic with hyperglycerolemia and hyperglyceroluria only. Similarity: Belongs to the FGGY kinase family. Database links: Entrez Gene: 2710 Human Entrez Gene: 14933 Mouse Omim: 300474 Human SwissProt: P32189 Human SwissProt: Q64516 Mouse Unigene: 1466 Human Unigene: 246682 Mouse Unigene: 225941 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |