| 產(chǎn)品編號(hào) | bs-2600R-BF488 |
| 英文名稱1 | Rabbit Anti-IL3R alpha/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的白介素3受體a鏈抗體 |
| 別 名 | IL-3R alpha; IL3R alpha; Interleukin-3 receptor subunit alpha precursor; CD 123; CD123; CD123 antigen; hIL3Ra; IL 3 receptor subunit alpha; IL 3R alpha; IL 3R; IL 3R subunit alpha; IL3 receptor subunit alpha; IL3R alpha; IL3R; IL3RAY; IL3RX; IL3RY; Interleukin 3 receptor alpha; Interleukin 3 receptor, alpha (low affinity); Interleukin-3 receptor; MGC34174; IL3RA_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-3R alpha |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012] Function: This is a receptor for interleukin-3. Subunit: Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. Subcellular Location: Membrane; Single-pass type I membrane protein. Similarity: Belongs to the type I cytokine receptor family. Type 5 subfamily. Database links: Entrez Gene: 3563 Human Omim: 308385 Human Omim: 430000 Human SwissProt: P26951 Human Unigene: 632790 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白細(xì)胞介素3受體α(IL-3Rα)又稱CD123，是造血生長(zhǎng)因子受體家族成員,CD123是未分化白血病干細(xì)胞的特異標(biāo)志.在細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)、細(xì)胞凋亡及血液腫瘤發(fā)生中起重要作用. |
