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Rabbit Anti-SOX6/Gold Conjugated antibody (bs-11599R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11599R-Gold
英文名稱1 Rabbit Anti-SOX6/Gold Conjugated antibody
中文名稱 膠體金標記的核轉錄因子SOX6抗體
別    名 HSSOX 6; HSSOX6; SOX-6 SOX 6; SOX6_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 神經生物學  信號轉導  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOX6 (1-100aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.

Subunit:
Interacts with DAZAP2

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in a wide variety of tissues, most abundantly in skeletal muscle.

Post-translational modifications:
Sumoylation inhibits the transcriptional activity.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 55553 Human

Entrez Gene: 20679 Mouse

Entrez Gene: 293165 Rat

Omim: 607257 Human

SwissProt: P35712 Human

SwissProt: P40645 Mouse

SwissProt: Q8BSS6 Mouse

SwissProt: Q4V8G3 Rat

Unigene: 368226 Human

Unigene: 323365 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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