產(chǎn)品編號(hào) | bs-11368R-PE-Cy5.5 |
英文名稱1 | Rabbit Anti-Sec8/PE-Cy5.5 Conjugated antibody |
中文名稱 | PE-Cy5.5標(biāo)記的胞吐分泌蛋白Sec8抗體 |
別 名 | dSec8; EXOC 4; Exoc4; EXOC4_HUMAN; Exocyst complex component 4; Exocyst complex component Sec8; KIAA1699; MGC27170; REC 8; REC8; rSec 8; Sec 8; Sec 8p; Sec8; SEC8 like 1; SEC8 protein; Sec8L1; Sec8p. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 110kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Sec8 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Subunit: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with BIRC6/bruce. Interacts with MYRIP. Similarity: Belongs to the SEC8 family. Database links: Entrez Gene: 60412 Human Entrez Gene: 20336 Mouse Omim: 608185 Human SwissProt: Q96A65 Human SwissProt: O35382 Mouse Unigene: 321273 Human Unigene: 265512 Mouse Unigene: 51841 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |