| 產(chǎn)品編號 | bs-11360R-BF488 |
| 英文名稱1 | Rabbit Anti-RIMS4/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的神經(jīng)元突觸膜胞外分泌調(diào)節(jié)蛋白4抗體 |
| 別 名 | C20orf190; dJ781B1.3; Rab3-interacting molecule 4; regulating synaptic membrane exocytosis 4; Regulating synaptic membrane exocytosis protein 4; RIM 4; RIM4 gamma; Rims4; RIMS4_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞類型標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RIMS4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Rim4 (Rab 3 interacting molecule 4), also known as Rim4 or regulating synaptic membrane exocytosis protein 4, is a 269 amino acid protein that localizes to the cell junction and regulates synaptic membrane exocytosis. Rab 3, a neural/neuroendocrine-specific member of the Rab family, is involved in Ca2+-regulated exocytosis. Rab 3 functions in an inhibitory capacity by controlling the recruitment of secretory vesicles into a releasable pool at the plasma membrane. Rim (Rab 3 interacting molecule), a putative effector protein for Rab 3 proteins, is thought to regulate neutrotransmitter release through its interaction with Rab 3 and other synaptic proteins. Function: Regulates synaptic membrane exocytosis. Subunit: Binds PPFIA3 (By similarity). Does not bind RAB3. Subcellular Location: Cell junction; synapse. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 C2 domain. Database links: UniProtKB/Swiss-Prot: Q9NYW1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
