產(chǎn)品編號(hào) | bs-11105R-Gold |
英文名稱1 | Rabbit Anti-Ninjurin 1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的神經(jīng)損傷誘導(dǎo)蛋白1抗體 |
別 名 | Nerve injury induced protein 1; Nerve injury-induced protein 1; NIN1; NINJ1; NINJ1_HUMAN; NINJURIN; Ninjurin-1. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 16kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Ninjurin 1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Ninjurin family proteins are muli-pass membrane proteins induced by nerve injury in Schwann cells and dorsal root ganglion neurons. Nunjurin proteins act as homophilic cell adhesion molecules that promote axonal growth. Ninjurin proteins also play a role in the formation and function of other tissues. Ninjurin-1 is widely expressed in adult and embryonic tissues, particularly those with epithelial origin. Ninjurin-2 is also widely expressed, with highest levels in adult bone marrow and peripheral blood lymphocytes and embryo liver, thymus and heart. The genes that encode the Ninjurin proteins map to a region known to cause several genetic disorders, including hereditary sensory neuropathy type I and type II (HSN1 and HSN2). However, no link between mutations in the genes encoding Ninjurins and the diseases have been found. Function: Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin. Similarity: Belongs to the ninjurin family. Database links: UniProtKB/Swiss-Prot: Q92982.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |