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Rabbit Anti-Estrogen Sulfotransferase/Gold Conjugated antibody (bs-0629R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0629R-Gold
英文名稱1 Rabbit Anti-Estrogen Sulfotransferase/Gold Conjugated antibody
中文名稱 膠體金標記的雌激素硫酸轉(zhuǎn)移酶抗體
別    名 Estrogen Sulfotransferase; Ste; SULT1E1; Estrogen sulfotransferase, testis isoform; Sulfotransferase, estrogen-preferring; EST; EST1; STE; sulfotransferase family 1E, estrogen-preferring, member 1; Sulfotransferase estrogen preferring; ST1E1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 免疫學  生長因子和激素  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Estrogen Sulfotranferase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.

Function:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Liver, intestine and at lower level in the kidney.

Similarity:
Belongs to the sulfotransferase 1 family.

Database links:

Entrez Gene: 6783 Human

Entrez Gene: 25355 Rat

Omim: 600043 Human

SwissProt: P49888 Human

SwissProt: P52844 Rat

Unigene: 479898 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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