| 產(chǎn)品編號 | bs-1882R-PE |
| 英文名稱1 | Rabbit Anti-MRas/PE Conjugated antibody |
| 中文名稱 | PE標(biāo)記的原癌基因M-ras抗體 |
| 別 名 | Mras; M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRAS |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling. Function: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Tissue Specificity: Expression highly restricted to the brain and heart. Similarity: Belongs to the small GTPase superfamily. Ras family. Database links: Entrez Gene: 22808 Human Entrez Gene: 17532 Mouse Omim: 608435 Human SwissProt: O14807 Human SwissProt: O08989 Mouse Unigene: 527021 Human Unigene: 2045 Mouse Unigene: 10641 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. M-ras癌變基因的表達產(chǎn)物Ras蛋白存在于多數(shù)腫瘤之中，目前是腫瘤研究較重要的蛋白之一. |
