產(chǎn)品編號(hào) | bs-6673R-AP |
英文名稱1 | Rabbit Anti-GIRK3/AP Conjugated antibody |
中文名稱 | 堿性磷酸酶(AP)標(biāo)記的G蛋白激活內(nèi)向鉀通道3抗體 |
別 名 | G protein activated inward rectifier potassium channel 3; G protein coupled inward rectifier potassium channel; G protein-activated inward rectifier potassium channel 3; GIRK-3; GIRK3; Inward rectifier K(+) channel Kir3.3; Inwardly rectifier K(+) channel Kir3.3; Inwardly rectifier K+ channel KIR3.3; inwardly rectifying subfamily J member 9; IRK9_HUMAN; Kcnj9; KIR3.3; Potassium channel; Potassium channel inwardly rectifying subfamily J member 9; Potassium inwardly rectifying channel subfamily J member 9; Potassium inwardly rectifying channel subfamily J9. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白 G蛋白偶聯(lián)受體 細(xì)胞表面分子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, ) |
產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 43kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GIRK3/KCNJ9 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Function: This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Subunit: Associates with GIRK1 to form a G-protein-activated heteromultimer pore-forming unit Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily. Database links: UniProtKB/Swiss-Prot: Q92806.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |