產(chǎn)品編號 | bs-1711R-PE |
英文名稱1 | Rabbit Anti-PCDA6/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的鈣粘蛋白相關(guān)的神經(jīng)受體2抗體 |
別 名 | Cadherln-related neuronal receptor2; Cadherin related neuronal receptor 2; CNR 2; CNR2; CNRN 2; CNRN2; CNRS 2; CNRS2; CRNR 2; CRNR2; KIAA0345 like 8; PCDH alpha6; PCDHA 6; PCDHA-6; PCDA6_HUMAN; PCDH-alpha-6; PCDHA6; Protocadherin alpha-6; Protocadherin alpha 6. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細胞骨架 細胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 100kDa |
細胞定位 | 細胞膜 |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CNR-2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008] Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subunit: Contains 6 cadherin domains. Subcellular Location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted (Potential). Similarity: Contains 6 cadherin domains. Database links: Entrez Gene: 56142 Human Omim: 606312 Human SwissProt: Q9UN73 Human Unigene: 199343 Human Unigene: 570901 Human Unigene: 599714 Human Unigene: 621225 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |