| 產(chǎn)品編號(hào) | bs-1518R-BF647 |
| 英文名稱1 | Rabbit Anti-Persephin/BF647 Conjugated antibody |
| 中文名稱 | BF647標(biāo)記的PSP抗體 |
| 別 名 | PSPN_HUMAN; PSP. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 生長(zhǎng)因子和激素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Persephin |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Elevated expression of this gene has been observed in oral squamous cell carcinoma. [provided by RefSeq, Aug 2016] Function: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. Similarity: Belongs to the TGF-beta family. GDNF subfamily. Database links: Entrez Gene: 5623 Human Omim: 602921 Human SwissProt: O60542 Human Unigene: 248159 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 神經(jīng)生物學(xué)相關(guān)蛋白（Neurobiology） PSP是TGF-β家族的一個(gè)新亞族，該亞族還有其他三個(gè)成員：Neurturin(NTN)、GDNF和Artemin(ART)，它們均不同程度地對(duì)多巴胺神經(jīng)元、脊髓前角運(yùn)動(dòng)神經(jīng)元、背根神經(jīng)節(jié)、頸上神經(jīng)節(jié)以及腎等非神經(jīng)元細(xì)胞都具有生長(zhǎng)促進(jìn)作用。研究表明膠質(zhì)細(xì)胞系源性神經(jīng)營(yíng)養(yǎng)因子,主要用于PD的研究。 |
