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Rabbit Anti-NIT2/Gold Conjugated antibody (bs-2012R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-2012R-Gold
英文名稱1 Rabbit Anti-NIT2/Gold Conjugated antibody
中文名稱 膠體金標記的NIT2蛋白抗體
別    名 Nitrilase family, member 2; Omega-amidase NIT2; Nitrilase homolog 2; 1190017B19Rik; D16ERTD502E; MGC111199; MGC124762; NIT2; RGD1310494; NIT2 protein; NIT2_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NIT2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
[FUNCTION] Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. [SUBUNIT] Homodimer. [SUBCELLULAR LOCATION] Cytoplasm. [TISSUE SPECIFICITY] Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon. [SIMILARITY] Belongs to the UPF0012 family.

Function:
Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon.

Similarity:
Belongs to the UPF0012 family.
Contains 1 CN hydrolase domain.

Database links:

Entrez Gene: 56954 Human

Entrez Gene: 52633 Mouse

SwissProt: Q9NQR4 Human

SwissProt: Q9JHW2 Mouse

Unigene: 439152 Human

Unigene: 383203 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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