產(chǎn)品編號(hào) | bs-1434R-BF488 |
英文名稱1 | Rabbit Anti-IGFBP3/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的胰島素樣生長因子結(jié)合蛋白3抗體 |
別 名 | IGF BP3; IGF-BP3; Acid stable subunit of the 140 K IGF complex; Binding protein 29; Binding protein 53; BP 53; BP53; Growth hormone dependent binding protein; IBP 3; IBP3; IGF binding protein 3; IGFBP 3;IGFBP-3; Insulin Like Growth Factor Binding Protein 3; IBP3_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 生長因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 糖尿病 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Rat, (predicted: Mouse, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 30-35kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human IGFBP3 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: GFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Subcellular Location: Secreted. Tissue Specificity: Expressed by most tissues. Present in plasma. Post-translational modifications: Phosphorylation sites are present in the extracelllular medium. Similarity: Contains 1 IGFBP N-terminal domain. Contains 1 thyroglobulin type-1 domain. Database links: Entrez Gene: 3486 Human Entrez Gene: 16009 Mouse Omim: 146732 Human SwissProt: P17936 Human SwissProt: P47878 Mouse Unigene: 450230 Human Unigene: 697535 Human Unigene: 29254 Mouse Unigene: 26369 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |