產(chǎn)品編號 | bs-1350R-Gold |
英文名稱1 | Rabbit Anti-DAP5/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的死亡相關(guān)蛋白5抗體 |
別 名 | DAP-5; DAP 5; Death Associated Protein-5; Death associated protein 5; Death-associated protein 5; eIF-4-gamma 2; eIF-4G 2; eIF4G 2; EIF4G2; Eukaryotic translation initiation factor 4 gamma 2; Nat1; Novel APOBEC-1 target 1; Translation repressor NAT1; IF4G2_HUMAN; p97. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號 細(xì)胞凋亡 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 102kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DAP-5 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitous. Database links: Entrez Gene: 1982 Human Entrez Gene: 13690 Mouse Omim: 602325 Human SwissProt: P78344 Human SwissProt: Q62448 Mouse Unigene: 183684 Human Unigene: 185453 Mouse Unigene: 103276 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. DAP-5又稱p97, 是白細(xì)胞轉(zhuǎn)移抑制因子4G (ELF4G)家族成員. DAP-5在各種種系表達(dá)廣泛并高度保守。 |