| 產(chǎn)品編號(hào) | bs-1318R-BF488 |
| 英文名稱(chēng)1 | Rabbit Anti-IL-5/BF488 Conjugated antibody |
| 中文名稱(chēng) | BF488標(biāo)記的白細(xì)胞介素5抗體 |
| 別 名 | B Cell Differentiation Factor I; IL5; IL 5; Colony stimulating factor; Colony Stimulating Factor Eosinophil; EDF; Eosinophil; Eosinophil Differentiation Factor; IL 5; Interleukin 5; B-cell differentiation factor I; IL-5; IL5_RAT; Interleukin-5; T Cell Replacing Factor; T-cell replacing factor; Interleukin5; TRF. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, ) |
| 產(chǎn)品應(yīng)用 | IF=1:200-800
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 13kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse IL-5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Interleukin 5 is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide linked homodimeric glycoprotein with 115 amino acid residues in each chain. Known also as EDF (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two domain structure, with each domain showing significant homology to the cytokine fold in GMCSF, MCSF, IL2, IL4 and growth hormone. Human and mouse IL5 have 70% amino acid sequence homology. Function: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. Similarity: Belongs to the IL-5 family. Database links: Entrez Gene: 3567 Human Omim: 147850 Human SwissProt: P05113 Human Unigene: 2247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白細(xì)胞介素-5（IL-5）的表達(dá)對(duì)嗜酸粒細(xì)胞（EOS）有浸潤(rùn)聚集的作用，目前多用變態(tài)反應(yīng)方面的研究。 支氣管哮喘的重要特征主要是慢性非特異性炎癥改變，其病因與發(fā)病機(jī)制十分復(fù)雜，白介素5在支氣管哮喘發(fā)病機(jī)理上，近年來(lái)受到了很大關(guān)注。 |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Rat small intestine); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation: Anti-IL-5 Antibody, conjugated (bs-1318R-BF488) 1:400, 1.5 hours at 37°C; DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.
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