產(chǎn)品編號 | bs-6507R-Gold |
英文名稱1 | Rabbit Anti-MTCBP1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的膜型基質(zhì)金屬蛋白酶胞質(zhì)尾結(jié)合蛋白1抗體 |
別 名 | ADI 1; Adi1; Adi-1; ADI1 antibody; APL1; ARD; EC 1.13.; Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; MTCBP 1; MTCBP-1; MTCBP1; MTND_HUMAN; Ni-ARD; SIPL; Submergence induced protein 2 homolog; Submergence-induced protein 2 homolog; 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Aci reductone dioxygenase; Acireductone dioxygenase (Ni(2+)-requiring); Acireductone dioxygenase 1 |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 信號轉(zhuǎn)導(dǎo) 腫瘤細(xì)胞生物標(biāo)志物 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 23kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MTCBP1/ADI1 (81-126aa) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: his gene encodes an enzyme that belongs to theaci-reductone dioxygenase family of metal-binding enzymes, whichare involved in methionine salvage. This enzyme may regulate mRNAprocessing in the nucleus, and may carry out different functionsdepending on its localization. Related pseudogenes have beendefined on chromosomes 8 and 20. Function: Catalyzes the formation of formate and2-keto-4-methylthiobutyrate (KMTB) from1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Alsodown-regulates cell migration mediated by MMP14. Necessary forhepatitis C virus replication in an otherwise non-permissive cellline. Subunit: Monomer (By similarity). Interacts with MMP14. Subcellular Location: Cytoplasm. Nucleus. Cell membrane;Peripheral membrane protein; Cytoplasmic side. Note=Localizes tothe plasma membrane when complexed to MMP14. Tissue Specificity: Detected in heart, colon, lung, stomach,brain, spleen, liver, skeletal muscle and kidney. Similarity: Belongs to the acireductone dioxygenase (ARD) family. Database links: UniProtKB/Swiss-Prot: Q08554.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |