產(chǎn)品編號 | bs-6218R-Cy7 |
英文名稱1 | Rabbit Anti-RAR gamma/Cy7 Conjugated antibody |
中文名稱 | Cy7標(biāo)記的維甲酸受體γ抗體 |
別 名 | NR1B3; Nuclear receptor subfamily 1 group B member 3; RAR gamma; RARC; RARG; Retinoic acid receptor gamma 1; Retinoic acid receptor gamma 2; Retinoic acid receptor gamma; Retinoic acid receptor gamma polypeptide; Retinoic acid receptor, gamma; RARG_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 50kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Retinoic Acid Receptor gamma |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Subunit: Homodimer. Heterodimer with a RAR molecule (By similarity). Binds DNA preferentially as a RAR/RXR heterodimer. Subcellular Location: Nucleus. Similarity: Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain. Database links: Entrez Gene: 5916 Human Entrez Gene: 19411 Mouse Omim: 180190 Human SwissProt: P13631 Human SwissProt: P18911 Mouse Unigene: 1497 Human Unigene: 733399 Human Unigene: 1273 Mouse Unigene: 198797 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |