產(chǎn)品編號 | V7505 |
英文名稱 | Human HE4 |
中文名稱 | 附睪分泌蛋白4單克隆抗體 |
別 名 | WFDC2 WAP four-disulfide core domain 2; dJ461P17.6; EDDM4; epididymal protein 4; Epididymal secretory protein E4; Epididymis specific whey acidic protein type four disulfide core; HE 4; Major epididymis specific protein E4; Major epididymis-specific protein E4; MGC57529; Putative protease inhibitor WAP5; WAP 5; WAP domain containing protein HE4; WAP four disulfide core domain 2; WAP four disulfide core domain protein 2; WAP four-disulfide core domain protein 2; WAP5; WFDC 2; WFDC2; WFDC2_HUMAN. |
克 隆 號 | 9D3 |
理論分子量 | 13kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | >1mg/ml |
緩 沖 液 | 0.01M PBS (pH7.4). |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008] Function: Broad range protease inhibitor. Subcellular Location: Secreted Tissue Specificity: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. Similarity: Contains 2 WAP domains. SWISS: Q14508 Gene ID: 10406 Database links: Entrez Gene: 10406 Human SwissProt: Q14508 Human Unigene: 2719 Human |