| 產(chǎn)品編號 | V4101 |
| 英文名稱 | Human PGI |
| 中文名稱 | 人胃蛋白酶原單克隆抗體 |
| 別 名 | Pepsin A-4; PEPA4_HUMAN; PGA4; pepsinogen 4, group I (pepsinogen A); Pepsin A 4; Pepsinogen-4 |
| 克 隆 號 | 4A8 |
| 理論分子量 | 42kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 緩 沖 液 | 0.01M PBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, and although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. The amino acid composition of Pepsin C differs from those of pepsinogen and pepsin especially in the content of basic amino acids, glutamic acid, aspartic acid, leucine and isoleucine. Function: Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. Subcellular Location: Secreted. Similarity: Belongs to the peptidase A1 family. SWISS: P0DJD7 Gene ID: 643847 Database links: Entrez Gene: 643847 Human
SwissProt: P0DJD7 Human |
