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Rabbit Anti-Phospho-TAK1(Thr184 + Thr187), BF680 conjugated antibody (bs-3439R-BF680)  
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說明書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3439R-BF680
英文名稱 Rabbit Anti-Phospho-TAK1(Thr184 + Thr187), BF680 conjugated antibody
中文名稱 BF680標記的磷酸化轉化生長因子β活化激酶1抗體
別    名 TAK1(Phospho T184 + T187); TAK1(Phospho Thr184 + Thr187); MAP3K7; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1; MAP3K 7; MAPKKK7; Mitogen activated protein kinase kinase kinase 7; TAK1; TGF beta activated kinase 1; TGF1a; Transforming growth factor beta activated kinase 1; M3K7_HUMAN; Map3k7; MEKK7; TGF-beta-activated kinase 1; TGF1a; Transforming growth factor-beta-activated kinase 1.  
產品類型 磷酸化抗體 
研究領域 腫瘤  免疫學  信號轉導  細胞凋亡  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 67kDa
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human TAK1 around the phosphorylation site of Thr184/187: IQ(p-T)HM(p-T)NN 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

SWISS:
O43318

Gene ID:
6885

Database links:

Entrez Gene: 6885 Human

Entrez Gene: 26409 Mouse

Entrez Gene: 313121 Rat

Omim: 602614 Human

SwissProt: O43318 Human

SwissProt: Q62073 Mouse

SwissProt: P0C8E4 Rat

Unigene: 722892 Human

Unigene: 258589 Mouse

Unigene: 24019 Rat



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