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Rabbit Anti-HMGB2  antibody (bsm-60675R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  
50ul/1580.00元
100ul/2500.00元
大包裝/詢價

產(chǎn)品編號 bsm-60675R
英文名稱 Rabbit Anti-HMGB2  antibody
中文名稱 高遷移率族蛋白2重組兔單抗
別    名 High mobility group (nonhistone chromosomal) protein 2; High mobility group box 2; High mobility group protein 2; High mobility group protein B2; HMG 2; HMG B2; HMG-2; HMG2; HMGB2_HUMAN.  
研究領(lǐng)域 腫瘤  信號轉(zhuǎn)導(dǎo)  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 R4C12
交叉反應(yīng) (predicted: Human,Mouse,Rat)
產(chǎn)品應(yīng)用 WB=1:500-1000,IHC-P=1:100-500,IHC-F=1:50-100,ICC/IF=1:50,IF=1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 24kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HMGB2 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]


Subcellular Location:
Nucleus. ChromosomeEntrez Gene: 3148 Human Entrez Gene: 540444 Cow Entrez Gene: 97165 Mouse SwissProt: P40673 Cow SwissProt: P26583 Human SwissProt: P30681 Mouse

SWISS:
P26583

Gene ID:
3148

Database links:


Entrez Gene: 3148 Human

Entrez Gene: 540444 Cow

Entrez Gene: 97165 Mouse

SwissProt: P40673 Cow

SwissProt: P26583 Human

SwissProt: P30681 Mouse




產(chǎn)品圖片
Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: HeLa, 2: HepG2, 3: PC-12 Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 24 kDa Observed MW: 24 kDa
Tissue: Rat cerebrum Section type: Formalin-fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to use) Counter stain: Hematoxylin (Blue) Comment: Color brown is the positive signal for bsm-60675R
Tissue: Mouse testis Section type: Formalin-fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to use) Counter stain: Hematoxylin (Blue) Comment: Color brown is the positive signal for bsm-60675R
Tissue: Human colon Section type: Formalin-fixed & Paraffin -embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to use) Counter stain: Hematoxylin (Blue) Comment: Color brown is the positive signal for bsm-60675R
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