產(chǎn)品編號(hào) | bsm-52587R |
英文名稱 | Rabbit Anti-ACKR3 antibody |
中文名稱 | 細(xì)胞表面趨化因子受體7重組兔單抗 |
別 名 | GPCR RDC1; C X C chemokine receptor type 7; Chemokine C X C motif receptor 7; Chemokine orphan receptor 1; CMKOR1; CXC R7; CXCR 7; CXCR7; G protein coupled receptor 159; G protein coupled receptor RDC1 homolog; GPR159; RDC 1; RDC1; CXCR7_HUMAN. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 G蛋白偶聯(lián)受體 |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 2G5 |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 40kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 細(xì)胞外基質(zhì) |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ACKR3 : 300-362/362 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. GCPR RDC1 is reported to be expressed in human cell lines and in cultured vascular endothelial cells and in rodent brain, kidney, lung, heart, spleen, pancreas, small intestine, blood, colon, and blood vessels. ESTs have been isolated from human normal bone marrow, brain, breast, cartilage, embryo, eye, fetal lung/testis/B-cell, heart, heart/melanocyte/uterus, kidney, liver/spleen, nerve, placenta, and umbilical libraries as well as several human cancer libraries. SWISS: P25106 Gene ID: 57007 Database links: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. GCPR RDC1 is reported to be expressed in human cell lines and in cultured vascular endothelial cells and in rodent brain, kidney, lung, heart, spleen, pancreas, small intestine, blood, colon, and blood vessels. ESTs have been isolated from human normal bone marrow, brain, breast, cartilage, embryo, eye, fetal lung/testis/B-cell, heart, heart/melanocyte/uterus, kidney, liver/spleen, nerve, placenta, and umbilical libraries as well as several human cancer libraries. |