產(chǎn)品編號 | bsm-51330M |
英文名稱 | Mouse Anti-S100A2 antibody |
中文名稱 | S100A2單克隆抗體 |
別 名 | S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 結(jié)合蛋白 細(xì)胞分化 |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 7G5 |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:20-50,ICC/IF=1:20-50,IF=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 11kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human S100A2 |
亞 型 | |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer. Function: May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth. Subunit: Homodimer. Interacts with FKBP4. Tissue Specificity: A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes. Similarity: Belongs to the S-100 family Contains 2 EF-hand domains. SWISS: P29034 Gene ID: 6273 Database links: Entrez Gene: 6273 Human Entrez Gene: 628324 Mouse Omim: 176993 Human SwissProt: P29034 Human Unigene: 516484 Human Unigene: 489562 Mouse |