| 產(chǎn)品編號 | bs-24303R |
| 英文名稱 | Rabbit Anti-Cadherin 16 antibody |
| 中文名稱 | 鈣粘蛋白16抗體 |
| 別 名 | CAD16_HUMAN; Cadherin kidney ; Cadherin-16; CDH 16; CDH16; Kidney cadherin; Kidney specific cadherin; Kidney-specific cadherin; Ksp cadherin; Ksp-cadherin; PRO1340; UNQ695. |
| 研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 90kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cadherin 16: 261-360/829 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011] Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Subcellular Location: Cell membrane. Tissue Specificity: Kidney specific. Similarity: Contains 6 cadherin domains. SWISS: O75309 Gene ID: 1014 Database links: Entrez Gene: 1014 Human Entrez Gene: 12556 Mouse Entrez Gene: 100328594 Rabbit Omim: 603118 Human SwissProt: O75309 Human SwissProt: O88338 Mouse SwissProt: Q28634 Rabbit Unigene: 513660 Human Unigene: 19423 Mouse Unigene: 3478 Rat |
| 產(chǎn)品圖片 |
Sample:
A549(Human) Cell Lysate at 30 ug
Primary: Anti-Cadherin 16 (bs-24303R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 90 kD
Observed band size: 95 kD
|
