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Rabbit Anti-FS/Follistatin  antibody (bs-21618R )  
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產(chǎn)品編號 bs-21618R
英文名稱 Rabbit Anti-FS/Follistatin  antibody
中文名稱 促卵泡激素抑釋素/卵泡抑素抗體
別    名 Activin binding protein; FS; Follistatin; Activin-binding protein; FS; fst; FST_HUMAN; Human follistatin gene; follistatin isoform FST344 precursor; FST344; follistatin isoform FST317 precursor; FST317; FST_HUMAN.  
Specific References  (2)     |     bs-21618R has been referenced in 2 publications.
[IF=5.834] Jie Pei. et al. A single-cell transcriptomic atlas characterizes cell types and their molecular features in yak ovarian cortex. FASEB J. 2022 Dec;37(1):e22718  IF ;  Yak.  
[IF=3.998] A. Ikeda. et al. Follistatin expressed in mechanically-damaged salivary glands of male mice induces proliferation of CD49f + cells. Sci Rep-Uk. 2020 Nov;10(1):1-14  IHC ;  Mouse.  
研究領(lǐng)域 免疫學(xué)  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Pig,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FS/Follistatin: 91-190/344 
亞    型 IgG
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]

Subunit:
Monomer (Potential).

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.

Similarity:
Contains 3 follistatin-like domains.
Contains 3 Kazal-like domains.
Contains 1 TB (TGF-beta binding) domain.

SWISS:
P19883

Gene ID:
10468

Database links:

Entrez Gene: 396119 Chicken

Entrez Gene: 327681 Cow

Entrez Gene: 10468 Human

Entrez Gene: 14313 Mouse

Entrez Gene: 445002 Pig

Entrez Gene: 24373 Rat

Omim: 136470 Human

SwissProt: Q90844 Chicken

SwissProt: P50291 Cow

SwissProt: P19883 Human

SwissProt: P47931 Mouse

SwissProt: P10669 Pig

SwissProt: P21674 Rat

Unigene: 9914 Human

Unigene: 4913 Mouse

Unigene: 162557 Rat



促卵泡激素抑釋素/卵泡抑素: 腦垂體細(xì)胞分泌的一種糖蛋白??膳c促卵泡激素釋放素/紅細(xì)胞分化因子發(fā)生特異結(jié)合,抑制腦垂體分泌促卵泡激素。
產(chǎn)品圖片
Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti-Follistatin (bs-21618R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 38 kD
Sample: Bone (Mouse) Lysate at 40 ug Primary: Anti- FS/Follistatin (bs-21618R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kD Observed band size: 41 kD
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